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Mississippi Pot Roast Instant Pot

Mississippi Pot Roast Instant Pot Recipe: A Flavorful and Easy Delight

"Make the BEST Mississippi Pot Roast in an Instant Pot—tender, flavorful, and ready in under 2 hours! Includes step-by-step instructions, tips, and variations."
Prep Time 10 minutes
Cook Time 1 hour 15 minutes
Total Time 1 hour 25 minutes
Course Appetizer, Main Course, Side Dish
Cuisine American
Servings 6 People
Calories 420 kcal

Ingredients
  

Core Ingredients

  • Chuck roast – 3–4 lbs - well-marbled for tenderness
  • Pepperoncini peppers – ½ cup sliced + ¼ cup juice - from a 16 oz jar
  • Au jus gravy mix – 1 packet - 1 oz
  • Ranch seasoning mix – 1 packet - 1 oz
  • Unsalted butter – ½ cup - 1 stick (or use salted, but reduce added salt)
  • Beef broth – ½ cup - low-sodium recommended

Essential Extras

  • Olive oil – 1 tbsp - for searing
  • Salt & black pepper – to taste - for seasoning roast
  • Garlic – 4 cloves - minced (optional but recommended)

Optional Add-Ins

  • Onion – 1 sliced - yellow or white
  • Carrots – 1 cup - chopped (adds sweetness)
  • Potatoes – 2 cups - cubed (for a one-pot meal)
  • Red pepper flakes – ½ tsp - for heat

Instructions
 

Sear the Roast

  • Set Instant Pot to "Sauté" mode and heat 1 tbsp oil.
  • Pat the roast dry, season with salt & pepper, then sear 3-4 minutes per side until browned.

Add Seasonings & Liquids

  • Pour in beef broth to deglaze the pot, scraping up browned bits.
  • Sprinkle au jus & ranch seasoning over the roast.
  • Add pepperoncinis + juice, butter, and garlic.

Pressure Cook

  • Secure the lid, set valve to "Sealing", and cook on "High Pressure" for:
  • 60 minutes (for 3 lbs roast)
  • 75 minutes (for 4 lbs roast)
  • Allow a 15-minute natural release, then quick-release remaining pressure.

Shred & Serve

  • Transfer roast to a plate and shred with forks.
  • Optionally, thicken the juices into gravy by mixing in a cornstarch slurry (1 tbsp cornstarch + 2 tbsp water) and simmering on "Sauté" mode.